As the 8th largest private employer in New York State, the University of Rochester (UR) is not only the largest regional employer, but the catalyst for over 50,000 jobs overall. In the two years since our previous study, it has continued to expand its influence by establishing affiliations with Thompson Health in Canandaigua, NY and the Pluta Cancer Center. It took over operations of the former Lakeside Medical Center facilities in Brockport, NY and has been a champion for economic development in the Mt. Hope Neighborhood. Its River and Medical Campuses continue to grow with new academic and medical buildings supporting cutting edge research and advanced medical care. UR attracts an average of $407 million per year in external grant funding which is expected to more than double over the next ten years with the launch of the new Institute for Data Science (IDS). The IDS will give the UR capacity in the field of “big data” available in only a handful of institutions nationally. In 2013, UR paid more than $1.5 billion in wages; spent an average of $241 million per year on capital projects; purchased $196 million in goods and services in the Rochester Metropolitan Area; and drew visitors that booked more than 24,700 hotel reservations.